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U2 small nuclear RNA auxiliary factor 1 : ウィキペディア英語版 | U2 small nuclear RNA auxiliary factor 1
Splicing factor U2AF 35 kDa subunit is a protein that in humans is encoded by the ''U2AF1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7307 )〕 == Function ==
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「U2 small nuclear RNA auxiliary factor 1」の詳細全文を読む
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